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Gene Therapy
Gene Therapy
Intrasplenic electro-transfer of IL-4 encoding plasmid DNA efficiently inhibits rat experimental allergic encephalomyelitis
Skeletal muscle biology / Gene Therapy / DNA / Spleen / Autoimmune Disease / Electroporation / Animals / Spinal Cord / Plasmids / Rats / Experimental Autoimmune Encephalomyelitis / Plasmid DNA / Control Group / Biochemistry and cell biology / Gene Transfer / Interleukin / Interferon gamma / Electroporation / Animals / Spinal Cord / Plasmids / Rats / Experimental Autoimmune Encephalomyelitis / Plasmid DNA / Control Group / Biochemistry and cell biology / Gene Transfer / Interleukin / Interferon gamma
Intracisternal rSV40 administration provides effective pan-CNS transgene expression
Genetics / Gene Therapy / Immunohistochemistry / Oxidative Stress / Apoptosis / HIV / Biological Sciences / Female / Animals / Gene transfer techniques / Glutathione Peroxidase / Central Nervous System / Neurons / Superoxide Dismutase / Gene Delivery / Rats / Transgene Expression / Mannitol / Gene Transfer / Neuroprotective Agents / HIV / Biological Sciences / Female / Animals / Gene transfer techniques / Glutathione Peroxidase / Central Nervous System / Neurons / Superoxide Dismutase / Gene Delivery / Rats / Transgene Expression / Mannitol / Gene Transfer / Neuroprotective Agents
Intracellular expression of antisense RNA transcripts complementary to the human immunodeficiency virus type-1 vif gene inhibits viral replication in infected T-lymphoblastoid cells
Gene Therapy / HIV / Cell line / Humans / Biochemical / T lymphocytes / Human immunodeficiency virus / Amino Acid Profile / Base Sequence / Antisense RNA / Biochemistry and cell biology / Nucleic Acid / Down-Regulation / T lymphocytes / Human immunodeficiency virus / Amino Acid Profile / Base Sequence / Antisense RNA / Biochemistry and cell biology / Nucleic Acid / Down-Regulation
Intracellular expression of antisense RNA transcripts complementary to the human immunodeficiency virus type-1 vif gene inhibits viral replication in infected T-lymphoblastoid cells
Gene Therapy / HIV / Cell line / Humans / Biochemical / T lymphocytes / Human immunodeficiency virus / Amino Acid Profile / Base Sequence / Antisense RNA / Biochemistry and cell biology / Nucleic Acid / Down-Regulation / T lymphocytes / Human immunodeficiency virus / Amino Acid Profile / Base Sequence / Antisense RNA / Biochemistry and cell biology / Nucleic Acid / Down-Regulation
Aplicación de tratamiento génico a un modelo subcutáneo de cáncer de pulmón murino
Gene Therapy / Lung Cancer / Dendritic cell / Clinical Sciences / Thymidine Kinase / Interleukin
Aplicación de tratamiento génico a un modelo subcutáneo de cáncer de pulmón murino
Gene Therapy / Lung Cancer / Dendritic cell / Clinical Sciences / Thymidine Kinase / Interleukin
El inicio de la vida humana Aspectos bioéticos de los nuevos avances científicos
Bioethics / Stem cell and Regenerative medicine / Contraception / Gene Therapy / Abortion / Eugenics / In Vitro Fertilisation / Emergency Contraception / Eugenics / In Vitro Fertilisation / Emergency Contraception
Intramyocardial transplantation of fibroblasts expressing vascular endothelial growth factor attenuates cardiac dysfunction
Gene Therapy / Biological Sciences / Cell therapy / Fibrin / Virus / Animals / Male / Heart / Cell Transplantation / VECTOR / Gene Delivery / Rats / Myocardial Infarction / Growth Factor / Human Fibroblasts / Ischemia–reperfusion / Transgene Expression / Left Ventricle / Gene Transfer / Vascular Endothelial Growth Factor / Animals / Male / Heart / Cell Transplantation / VECTOR / Gene Delivery / Rats / Myocardial Infarction / Growth Factor / Human Fibroblasts / Ischemia–reperfusion / Transgene Expression / Left Ventricle / Gene Transfer / Vascular Endothelial Growth Factor
Micro-dystrophin cDNA ameliorates dystrophic phenotypes when introduced into mdx mice as a transgene
Skeletal muscle biology / Fluorescence Microscopy / Gene Therapy / Immunohistochemistry / Western blotting / Transgenic Mice / Humans / Mice / Animals / Adeno-associated virus / Biochemical / Duchenne Muscular Dystrophy / Creatine Kinase / Phenotype / Skeletal Muscle / Time Factors / Dystrophin / Biochemistry and cell biology / Gene Transfer / Transgenic Mice / Humans / Mice / Animals / Adeno-associated virus / Biochemical / Duchenne Muscular Dystrophy / Creatine Kinase / Phenotype / Skeletal Muscle / Time Factors / Dystrophin / Biochemistry and cell biology / Gene Transfer
Adeno-associated virus vector-mediated gene transfer into dystrophin-deficient skeletal muscles evokes enhanced immune response against the transgene product
Immune response / Skeletal muscle biology / Gene Therapy / Biological Sciences / Mice / Female / Animals / Gene transfer techniques / Male / Immunosuppression / Adeno-associated virus / Duchenne Muscular Dystrophy / Skeletal Muscle / Degeneration / Dystrophin / Gene Transfer / Female / Animals / Gene transfer techniques / Male / Immunosuppression / Adeno-associated virus / Duchenne Muscular Dystrophy / Skeletal Muscle / Degeneration / Dystrophin / Gene Transfer
Transfection efficiency boost by designer multicomponent lipoplexes
Chemical Engineering / Clinical Trial / Gene Therapy / Small Angle X Ray Scattering / Biological Sciences / DNA / Cell line / Diffusion / Mice / Animals / Physical sciences / Liposomes / Structural Change / Gene Delivery / Transfection / Drug Carriers / Biochemistry and cell biology / DNA / Cell line / Diffusion / Mice / Animals / Physical sciences / Liposomes / Structural Change / Gene Delivery / Transfection / Drug Carriers / Biochemistry and cell biology
Gene transfer in ovarian cancer cells: a comparison between retroviral and lentiviral vectors
Cancer / Flow Cytometry / Gene Therapy / Confocal Microscopy / Ovarian Cancer / Gene expression / Quantitative analysis / real time PCR / Humans / Female / Gene transfer techniques / Lentivirus / Quantitative Analysis / Transgene Expression / Gene Transfer / Interferon Alpha / Gene expression / Quantitative analysis / real time PCR / Humans / Female / Gene transfer techniques / Lentivirus / Quantitative Analysis / Transgene Expression / Gene Transfer / Interferon Alpha
Intramyocardial transplantation of fibroblasts expressing vascular endothelial growth factor attenuates cardiac dysfunction
Gene Therapy / Biological Sciences / Cell therapy / Fibrin / Virus / Animals / Male / Heart / Cell Transplantation / VECTOR / Gene Delivery / Rats / Myocardial Infarction / Growth Factor / Human Fibroblasts / Ischemia–reperfusion / Transgene Expression / Left Ventricle / Gene Transfer / Vascular Endothelial Growth Factor / Animals / Male / Heart / Cell Transplantation / VECTOR / Gene Delivery / Rats / Myocardial Infarction / Growth Factor / Human Fibroblasts / Ischemia–reperfusion / Transgene Expression / Left Ventricle / Gene Transfer / Vascular Endothelial Growth Factor
Prostate targeting: PSP94 gene promoter/enhancer region directed prostate tissue-specific expression in a transgenic mouse prostate cancer model
Clinical Trial / Gene Therapy / Immunohistochemistry / Prostate Cancer / Cell Culture / Transgenic Mice / Biological Sciences / Mice / Animals / Male / Gene Targeting / Disease Progression / Amino Acid Profile / Transgenic Mouse Technology / Tumor Progression / Tissue Specificity / Transgenic Mice / Biological Sciences / Mice / Animals / Male / Gene Targeting / Disease Progression / Amino Acid Profile / Transgenic Mouse Technology / Tumor Progression / Tissue Specificity
Combination Angiostatin and Endostatin Gene Transfer Induces Synergistic Antiangiogenic Activity in Vitro and Antitumor Efficacy in Leukemia and Solid Tumors in Mice
Technology / Flow Cytometry / Gene Therapy / Immunohistochemistry / Leukemia / Cell separation / Western blotting / Cell Division / Biological Sciences / Molecular / Humans / Collagen / Mice / Female / Melanoma / Animals / Gene transfer techniques / Plasminogen / Proteoglycans / Endothelial cell / Time Factors / Transfection / Antitumor Activity / Recombinant Protein / Cell Survival / Tumor Growth / Antineoplastic Agents / Molecular Targeted Therapy / Gene Transfer / Angiogenesis inhibitor / Cell Growth / Down-Regulation / Laminin / Cell separation / Western blotting / Cell Division / Biological Sciences / Molecular / Humans / Collagen / Mice / Female / Melanoma / Animals / Gene transfer techniques / Plasminogen / Proteoglycans / Endothelial cell / Time Factors / Transfection / Antitumor Activity / Recombinant Protein / Cell Survival / Tumor Growth / Antineoplastic Agents / Molecular Targeted Therapy / Gene Transfer / Angiogenesis inhibitor / Cell Growth / Down-Regulation / Laminin
Efficient introduction of plasmid DNA into human hemopoietic cells by encapsidation in simian virus 40 pseudovirions
Genetics / Gene Therapy / Multidisciplinary / Genetic Engineering / Cell line / Humans / Plasmids / Calcium Phosphate / High Efficiency / Capsid Protein / Plasmid DNA / Bone Marrow Cells / Humans / Plasmids / Calcium Phosphate / High Efficiency / Capsid Protein / Plasmid DNA / Bone Marrow Cells
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